Site-specific drug delivery and targeting attracts much research interest from both academia and industry, but because of the many challenges faced in the development of these systems, only a handful of targeted therapies have successfully made it into clinical practice. Focusing on the delivery technologies that utilize both systemic and local routes of administration, Targeted Delivery of Small and Macromolecular Drugs brings together field experts who summarize current progress and discuss novel ideas currently being explored to overcome these challenges. The contributors discuss the most promising strategies for drug targeting and also examine targeted drug delivery platforms and technologies at various stages of clinical and preclinical development, including: Active targetingNucleic acid delivery and targetingIntracellular/organelle-specific strategiesProdrug strategiesOrgan or tissue-specific drug deliveryDrug-polymer conjugates and micellesStimuli-responsive systemsThe book demonstrates why targeted delivery is one of the most exciting contributions pharmaceutical sciences can make to drug therapy.
